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    • 专利摘要:
    Skin Cleansing Composition The present invention relates to lamellar phase concentrated liquid cleansing compositions which have an appearance similar to the enhanced hydration signal transmission lotion. It has been found that the use of a specific ratio of synthetic anionic surfactant (s) and co-surfactant (s) to fatty acid (s) in a liquid product Structured enhances foam production by moderating or eliminating increased viscosity by dilution. In another embodiment, the specific small hydrophobic molecules have been found to improve freeze / thaw stability and thus cause the composition of the present invention to maintain the perceived signs of hydration.
    公开号:BR112015013023B1
    申请号:R112015013023-2
    申请日:2013-11-18
    公开日:2019-11-05
    发明作者:Kingston Shutak Alexander；Shiloach Anat；Sekhar Palla-Venkata Chandra；Andrew Early James；David Hermanson Kevin；Yang Lin；Mohanlal Dave Rajendra；Moaddel Teanoosh；Thomas Hu Yuntao
    申请人:Unilever Nv；
    IPC主号:
    专利说明:

    “SKIN CLEANING COMPOSITION”
    Field of the Invention [001] The present invention relates to concentrated liquid cleaning compositions suitable for topical application for cleaning the human body, such as skin and hair. In particular, it refers to a concentrated lamellar phase personal cleaning composition, which is capable of appreciably foaming and, in a preferred embodiment, resists freeze-thaw destabilization.
    Background of the Invention [002] Liquid concentrated lamellar phase cleaners are known. For example, US patents 7,884,060 and 7,884,061 filed on February 14, 2012 and patent 8,114,826, filed on February 8, 2011 all by Hermanson et. al., describe the preparation of concentrated formulations based on readily pumped soap, containing an amount greater than 40% of fatty acid (s).
    [003] US patent 7,879,781 filed in February 2011 by Patel et al., Describes the preparation of lamellar compositions of high emollients consisting of 2 to 4% lauric acid resistant to changes in viscosity under freezing cycles and thawing.
    [004] The rheological behavior of all surfactant solutions, which includes liquid cleaning solutions, is strongly dependent on the microstructure, for example, on the shape and concentration of the micelles and other self-organized structures in solution.
    [005] When there is enough surfactant to form the micelles (concentrations above the critical micellar concentration or CMC), for example, spherical, cylindrical (stick-type), or discoid micelles can form. As the surfactant concentration increases, the ordered liquid crystalline phases, such as the lamellar phase, hexagonal phase, cubic phase
    Petition 870190100374, of 10/07/2019, p. 10/123
    2/42 can form. The lamellar phase, for example, consists of alternating the surfactant bilayers and the water layers. These layers, in general, are not flat, but bend to form spherical submicron onion-like structures called vesicles or liposomes. The hexagonal phase, on the other hand, consists of long cylindrical micelles arranged in a hexagonal network. In general, the microstructure of most personal care products consists of spherical micelles; rod-like micelles; or a lamellar dispersion.
    [006] As noted above, the micelles can be spherical or stick-type. Formulations with spherical micelles tend to have a low viscosity and exhibit a Newtonian shear behavior (ie, viscosity remains constant as a function of the shear rate; therefore, if easy product flow is desired, the solution is less viscous and, as a consequence, also does not suspend). In these systems, viscosity increases linearly with the concentration of the surfactant.
    [007] Stick-type micellar solutions are more viscous, since the movement of longer micelles is restricted. At a critical shear rate, the micelles align and the solution becomes pseudoplastic. The addition of salts increases the size of the rod-like micelles by increasing the zero shear viscosity (that is, the viscosity when resting in the bottle) that helps to suspend the particles, but also increases the critical shear rate (point where the product becomes pseudoplastic; higher critical shear rates mean the product is more difficult to flow).
    [008] Lamellar dispersions differ from spherical and rod-like micelles, as they may have high zero-shear viscosity (due to the narrow droplet packing arrangement
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    3/42 lamellar constituents), but these solutions are very pseudoplastic (easily dispensed in the flow). That is, solutions can become thinner than rod-type micellar solutions at moderate shear rates.
    [009] Therefore, in the formulation of liquid cleaning compositions, there is the option of using stick-type micellar solutions (whose zero-shear viscosity, for example, suspend the possibility, is not very good and / or is not very pseudoplastic) ; or lamellar dispersions. (with shear viscosity greater than zero, for example, better suspension, and are still very pseudoplastic). Such lamellar compositions are characterized by shear viscosity greater than zero (good for suspension and / or structuring), while simultaneously being very pseudoplastic in such a way that it easily dispenses in the flow. These compositions have a “stacking” lotion-like appearance, which transmit the signs of enhanced hydration.
    [010] To form such lamellar compositions, however, some commitments need to be made. First, in general, higher amounts of surfactant are needed to form the lamellar phase. Therefore, it is often necessary to add auxiliary surfactants and / or salts that are neither desirable nor necessary. Second, only certain surfactants will form this phase and, therefore, the selection of surfactants is restricted.
    [011] In summary, lamellar compositions, in general, are more desirable (especially for the suspension of an emollient and to provide aesthetics for consumption), but more expensive, in that, in general, they require more surfactant and are more restricted in the range of surfactants that can be used.
    [012] When rod-type micellar solutions are used,
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    4/42 these also often require the use of external structuring agents to intensify the viscosity and suspend the particles (again, since they have less than zero shear viscosity than the lamellar phase solutions). For this, carbomers and clays are often used. At higher shear rates (such as when dispensing the product, applying the product to the body or rubbing with the hands), since the micellar stick-type solutions are less pseudoplastic, the viscosity of the solution remains high and the product can be sticky and thick. Lamellar dispersion products, which have a shear viscosity greater than zero, can more easily suspend emollients and are usually more creamy. Again, however, in general, they are more expensive to manufacture (for example, they are restricted to which surfactants can be used and often require a higher concentration of surfactants).
    [013] In general, lamellar phase compositions are easy to identify by their characteristic focal conical shape and texture with oily marks while the hexagonal phase exhibits the angular fan-like texture. In contrast, the micellar phases are ideally isotropic.
    [014] It should be understood that lamellar phases can be formed in a wide variety of surfactant systems using a wide variety of “lamellar” phase inductors, as described, for example, in US patent 5,952,286 entitled “Liquid Cleansing Composition Comprising Soluble, Lamellar Phase Inducing Structural ”by Sudhakar Puvvada, et al., Deposited on September 14, 1999. In general, the transition from the micellar to lamellar phase are functions of the effective mean area of the main group of the surfactant, the tail length extended, and the tail volume. The use of branched surfactants or surfactants with lower main groups or bulky tails are also effective ways of
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    5/42 induce micellar to lamellar transitions.
    [015] One way to characterize lamellar dispersions includes measuring the viscosity at a low shear rate (for example, using a Strain Rheometer) when the additional inductor (for example, oleic acid or isostearic acid) is used. In larger amounts of inductor, the low shear viscosity will increase significantly.
    [016] Another way to measure lamellar dispersions is by using freezing fracture electron microscopy. The micrographs, in general, will show the lamellar microstructure and the narrow organization of the lamellar droplets (in general, in the size range of about 2 microns).
    [017] A problem with certain lamellar phase compositions is that they tend to lose their lamellar stability at lower temperatures (for example, from -17 ° C to 7.2 ° C (0 to 45 ° F)). While not wishing to be bound by theory, this may be due, in cold conditions, that the oil droplets become less flexible and the spherical structure that characterizes the lamellar interaction breaks into sheets, rather than lamellae.
    [018] It was unexpectedly discovered that the specific concentrated lamellar cleaning compositions of the present invention provide consumers with (a) better sensory properties in use, such as creamy-looking foam and enhanced skin feel providing a hydrated feel to the skin (b) better performance, such as increasing the amount of foam and the speed of foam and (c), potentially offering a greater number of washes with a smaller package / product for the consumer. The present invention provides a concentrated cleaning composition, characterized by a smooth lamellar gel with a butterlike feel and good spreadability with high levels of fatty acid (s) in a range of specific proportions of synthetic anionic surfactants and co-surfactants. In an achievement
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    6/42 preferred, it was unexpectedly found that the composition of the present invention stabilizes against a marked loss of viscosity after freezing and thawing through a selection of small hydrophobic molecules.
    [019] Concentrated cleaning compositions are known to pass through undesirable, very viscous phases (cubic and hexagonal phases) before the less viscous, more desired, easy to handle lamellar phase is achieved after increasing the surfactant concentration (see, for example, example, US patent 2007 / 0.287.648 to Moaddel et al., incorporated herein by reference). Cotensoatives (defined herein as amphoteric or non-ionic surfactants or mixtures thereof) can be used to facilitate the formation of lamellar phases. In the concentrated formulations of the present invention, it was observed that a specific range of proportion of the synthetic anionic surfactant (s) and co-surfactant (s) of C12-C18 allows the formation of the phase lamellar and unexpectedly provides substantially improved foam volume and speed for defoaming. At these high levels of fatty acid content, although a smooth lamellar gel is formed, which is stable at room and elevated temperatures, an exceptionally wide drop in viscosity (greater than 95%) under freeze-thaw conditions was observed. In a preferred embodiment, it has unexpectedly been found that the addition of specific, small hydrophobic molecules, substantially improves the freeze-thaw stability of the high fatty acid containing the concentrated compositions that are essential for the beneficial use of the product consumer.
    Brief Description of the Invention [020] In one aspect of the present invention is an aqueous, structured, lamellar skin cleansing composition that includes but is not limited to:
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    7/42 (a) about 15 to 40% by weight of synthetic anionic surfactant (s);
    (b) about 5 to 30% by weight of the selected surfactant (s) from the group of amphoteric or non-ionic surfactants or their mixtures;
    (c) about 5 to 15% by weight of C12-C18 alkyl linear fatty acid (s);
    (d) where the proportion of synthetic anionic surfactant (s): co-surfactant (s) is about 0.5 to 3; and (e) where the proportion of synthetic anionic surfactant (s) and co-surfactant (s) to the linear alkyl fatty acid (s) C12-C18 is about 2 to 6.
    Detailed Description of the Invention [021] In one aspect, the present invention is an aqueous, structured, lamellar skin cleansing composition that includes but is not limited to:
    (a) about 15 to 40% by weight of synthetic anionic surfactant (s); preferably, a minimum of about 17.5 or 20% by weight and a maximum of about 30 or 35% by weight;
    (b) about 5 to 30% by weight of the selected surfactant (s) from the group of amphoteric or non-ionic surfactants or their mixtures; preferably, a minimum of about 7.5 or 10% by weight and a maximum of about 20 or 25% by weight; preferably, the co-active agent is sodium lauroyl anfoacetate, cocoamidopropyl betaine, cocamidopropyl hydroxyl sultaine or polyglucoside alkyl or mixtures thereof;
    (c) about 5 to 15% by weight of C12-C18 alkyl linear fatty acid (s); preferably lauric, myristic, palmitic or stearic acids, or mixtures thereof; preferably lauric acid; more preferably, greater than about 7 or 8% by weight and less than about 11 or 12% by weight.
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    8/42 (d) in which the proportion of synthetic anionic surfactant (s): co-surfactant (s) is about 0.5 to 3; preferably, a minimum of about 0.5, 0.55 or 0.6 and a maximum of about 2, 2.5 or 3; and (e) where the proportion of synthetic anionic surfactant (s) and co-surfactant (s) to the linear alkyl fatty acid (s) C12-C18 is about 2 to 6; preferably, from about 2 to 4; and, most preferably, from about 2 to 3.5.
    [022] Advantageously, the viscosity continually reduces or only slightly increases by not more than 3, 2 or 1 Pa.s as the composition of the present invention is diluted with water during cleaning and rinsing of the skin by a consumer. 40 ° C (hot water) compared to comparative compositions that show a significant increase in viscosity during dilution through washing and deleterious foam production / stability. Preferably the pH of the composition of the present invention is in the range of about 5 to 8, preferably of 5.5 to 7.7, and more preferably, of 6 to 7.5.
    [023] Preferably, the composition of the present invention further includes an effective amount of freeze-thaw stabilizer (s) selected from branched C6-C18 alkenes, branched C6-C18 alkenols, branched C6-C18 alkanes, branched C6-C18 alkanes , branched C6-C18 alkyl-aryl ethers, benzyl esters and mixtures thereof in a concentration effective to maintain at least 55% of the composition's viscosity after a freeze-thaw cycle using the standard freeze-thaw test. Most preferably, the freeze-thaw stabilizer (s) are present in a total concentration of about 0.5 to 5% by weight; most preferably, a minimum of about 1 or 1.5% by weight and a maximum of about 3 or 4% by weight.
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    9/42 [024] Most preferably, the freezing and thawing stabilizer (s) are selected from dihydromyrcenol, isooctanol, linalool, citronellol, 1-octene-3-ol, hexyl acetate, limonene, octylphenoxy polyethoxy ethanol (Igepal ® ), lillial, hexane, 1-octene, and benzyl salicylate and mixtures thereof.
    [025] Advantageously, the freeze-thaw stabilizer (s) of the present invention have an HLB value of less than about 5. Preferably, the freeze-stabilizer (s) - thawing has (in) an effective molecular length greater than about 5 but not greater than about 30 Angstroms. Preferably, the freeze-thaw stabilizer (s) has a melting point of less than 0 o C. Most preferably, the freeze-thaw stabilizer (s) of the present invention has (in), at least two of these properties and in a preferred embodiment it has (in) three of these properties.
    [026] In another preferred embodiment, the composition of the present invention includes about 0.5 to 3% by weight of 12-hydroxy stearic acid.
    [027] Preferably, the composition of the present invention includes non-occlusive emollients in the concentration range of about 0.5 to 25% by weight; preferably, a minimum of about 2.5 or 5% by weight and a maximum of about 15 or 20% by weight. Most preferably, non-occlusive emollients are selected from glycerin or 1,3 butanediol or mixtures thereof.
    [028] Preferably, the composition of the present invention includes occlusive emollients in the concentration range of about 0.5 to 25% by weight; preferably, a minimum of about 2.5 or 5% by weight and a maximum of about 15 or 20% by weight. Most preferably, occlusive emollients
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    10/42 are selected from mineral oils, tri and diglyceride oils, silicone oils, petroleum jelly, or paraffin wax or their mixtures.
    [029] Advantageously, the synthetic anionic surfactant (s) is (are) selected from sodium lauryl sulfate ether-1EO, 2EO and 3EO, acyl glycinate C12, directly esterified fatty isethionate (DEFI) or sodium trideceth sulfate or mixtures thereof and the co-activative (s) is (are) selected from cocoamidopropyl betaine (CAPB), anfoacetate, cocamidopropyl hydroxyl sultaine (CAPHS) alkyl polyglucoside (APG) or mixtures thereof.
    Surfactants [030] The synthetic anionic (s) and co-surfactant (s) is preferably included in the cleaning composition of the present invention. Surfactants are compounds that have hydrophobic and hydrophilic portions that act to reduce the surface tension of the aqueous solutions in which they are dissolved.
    Synthetic Anionic Surfactant (s) [031] The cleaning composition of the present invention preferably contains one or more non-soap synthetic anionic surfactant (s). Preferably, the synthetic anionic surfactant (s) is (are) used at levels as low as 15, 17.5 or 20% by weight and at levels as high as 30 , 35 or 40% by weight.
    [032] The active synthetic anionic detergent that can be used in the present invention can be aliphatic sulfonates, such as a primary alkane sulfonate (for example, C8-C22), primary alkane disulfonate (for example, C8-C22 ), C8-C22 alkene sulfonate, C8C22 hydroxyalkane sulfonate or alkyl glyceryl ether sulfonate (AGS); or an aromatic sulfonate, such as an alkyl benzene sulfonate. What it includes can also be an alkyl sulfate (for example, C12-C18 alkyl sulfate), or a sulfate of
    Petition 870190100374, of 10/07/2019, p. 10/21
    11/42 alkyl ether (which includes the glyceryl alkyl ether sulfates). Among the alkyl ether sulfates are those that have the Formula:
    - RO (CH2CH2O) nSO3M
    - where R is an alkyl or alkenyl containing 8 to 18 carbons, preferably 12 to 18 carbons, n has an average value greater than 1.0, preferably less than 3; and M is a solubilization cation, such as sodium, potassium, ammonium or substituted ammonium. Sulfates of ammonium ether and sodium lauryl are preferred.
    [033] Anionics can also be alkyl sulfosuccinates (which includes mono- and dialkyl, for example, C6-C22 sulfosuccinates); alkyl and acyl taurates, alkyl and acyl sarcosinates, sulfoacetates, C8-C22 alkyl phosphates and phosphates, alkyl phosphate esters and alkoxy alkyl phosphate esters, acyl lactates, C8-C22 monoalkyl succinates and maleates, sulfoacetates alkyl glycosides and acyl isethionates, and the like.
    [034] Sulfosuccinates can be monoalkyl sulfosuccinates with the Formula:
    - R 4 O2CCH2CH (SO3M) CO2M; and
    - MEA amide sulfosuccinates of Formula;
    - R 4 CONHCH2CH2O2CCH2CH (SO3M) CO2M
    - where R 4 varies from C8-C22 alkyl and M is a solubilization cation.
    [035] Sarcosinates, in general, are indicated by the Formula:
    - R1CON (CH3) CH2CO2M,
    - where R 1 varies from C8-C20 alkyl and M is a solubilization cation.
    [036] Taurates, in general, are identified by the Formula:
    - R 2 CONR 3 CH2CH2SO3M
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    - where R 2 varies from C8-C20 alkyl, R 3 varies from C1-C4 alkyl and M is a solubilization cation.
    [037] The cleaning composition of the present invention can contain the C8-C18 acyl isethionates. These esters are prepared by reacting the alkali metal isethionate with the mixture of aliphatic fatty acids containing 6 to 18 carbon atoms and an iodine index of less than 20. At least 75% of the mixed fatty acids contain 12 to 18 carbon atoms and up to 25% contain 6 to 10 carbon atoms.
    [038] Acyl isethionate may be an alkoxylated isethionate as described in Ilardi et al., US patent 5,393,466, entitled "Fatty Acid Esters of Polyalkoxylated isethonic acid '; filed on February 28, 1995; incorporated herein as a reference. This compound has the general formula:
    - R C-O (O) -C (X) H-C (Y) H2 (OCH-CH2) m-SO3M +
    - where R is an alkyl group containing 8 to 18 carbon atoms, m is an integer from 1 to 4, X and Y are hydrogen or an alkyl group containing 1 to 4 carbon atoms and M + is a cation monovalent, such as, for example, sodium, potassium or ammonium
    Amphoteric Surfactants [039] One or more amphoteric surfactant (s) can be used in the present invention as a co-surfactant. The amphoteric surfactant (s) is preferably used at levels as low as 57.5 or 10% by weight and at levels as high as 20, 25 or 30% in Weight. These surfactants include at least one acid group. This can be a group of carboxylic or sulfonic acid. They include quaternary nitrogen and are therefore quaternary amino acids. In general, they should include an alkyl or alkenyl group of 7 to 18 carbon atoms. Normally, they comply with a general structural Formula:
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    13/42
    - R 1 - [- C (O) -NH (CH2) n-] mN + - (R 2 ) (R 3 ) XY
    - where R 1 is an alkyl or alkenyl of 7 to 18 carbon atoms;
    - R 2 and R 3 are each independently an alkyl, hydroxyalkyl or carboxyalkyl group or of 1 to 3 carbon atoms;
    - n is 2 to 4;
    - m is 0 to 1;
    - X is alkylene of 1 to 3 carbon atoms optionally substituted with hydroxyl; and
    - Y is -C02- or -SO3- [040] Suitable amphoteric surfactants with the General Formula above include the simple Betaines of Formula:
    - R1-N + - (R 2 ) (R 3 ) CH2CO2 -
    - and the betaine starches of Formula:
    - R 1 - CONH (CH2) nN + - (R 2 ) (R 3 ) CH2CO2 -
    - where n is 2 or 3.
    [041] In the two Formulas, R 1 , R 2 and R 3 are as previously defined. R 1 , in particular, can be a mixture of C12-C14 alkyl groups derived from coconut oil so that at least half, preferably at least three-quarters of the R 1 groups have 10 to 14 carbon atoms . R 2 and R 3 are preferably methyl.
    [042] Another possibility is that the amphoteric detergent is a sulfobetaine of Formula:
    - R1-N + - (R 2 ) (R 3 ) (CH2) 3SO3 -
    - or
    - R 1 - CONH (CH2) mN + - (R 2 ) (R 3 ) (CH2) 3SO3 -
    - where m is 2 or 3, or its variants where - (CH2) 3 SO3 - is replaced by
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    - CH2C (OH) (H) CH2SO3 [043] In these Formulas, R 1 , R 2 and R 3 are as previously discussed.
    [044] Anphoacetates and dianfoacetates are also intended to be included in possible zwitterionic and / or amphoteric compounds that can be used such as, for example, sodium lauroamfoacetate, sodium cocoanfoacetate, and mixtures thereof, and the like.
    Non-ionic surfactants [045] One or more non-ionic surfactant (s) can be used in the cleaning composition of the present invention, such as a co-surfactant. Nonionic surfactants are preferably used at levels as low as 5, 7.5 or 10% by weight and at levels as high as 20, 25 or 30% by weight. The nonionic surfactants that can be used, in particular, include the reaction products of the compounds with a hydrophobic group and a reactive hydrogen atom, for example, aliphatic alcohols, acids, starches or alkylphenols with alkylene oxide, especially the ethylene oxide, alone or with propylene oxide. Specific non-ionic detergent compounds are condensates of ethylene oxide (C6-C22) phenols, condensation products of primary or secondary aliphatic (C8-C18) alcohols, linear or branched, with ethylene oxide and products produced through condensation of ethylene oxide with the reaction products of propylene oxide and ethylenediamine. Other so-called non-ionic detergent compounds include long-chain tertiary amine oxides, long-chain tertiary phosphine oxides and dialkyl sulfoxide, and the like.
    [046] Preferred non-ionic surfactants include alkyl polyglycoside ethoxylates and carboxylic acid / alcohol which have the following structures:
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    15/42 (a) HOCH2 (CH2) n (CH2CH2O) x H or (b) HOOC (CH2) m (CH2CH2O) y-H;
    - where m, n, independently, are less than 18; and x, y, independently, are greater than 1; preferably, m, n, independently, are 6 to 18; x, y, independently, are from 1 to 30;
    (c) HOOC (CH2) i-CH = CH- (CH2) k (CH2CH2O) Z H;
    - where i, k, independently, are 5 to 15; and Z, independently, is 5 to 50; preferably i, k, independently, are 6 to 12; and z, independently, is 15 to 35.
    [047] The non-ionic surfactant can also be a sugar amide, such as a polysaccharide amide. Specifically, the surfactant may be one of the lactobionamides described in US patent 5,389,279 to Au et al., Entitled “Compositions Comprising Nonionic Glycolipid Surfactants”, filed on February 14, 1995, which is incorporated herein as a reference or may be one the sugar amides described in US Patent 5,009,814 to Kelkenberg, entitled “Use of N-PoIy Hydroxyalkyl Fatty Acid Amides as Thickening Agents for Liquid Aqueous Surfactant Systems”, filed April 23, 1991; incorporated in this patent application as a reference.
    Normal Carboxylic Acids [048] C12-C18 alkyl carboxylic acid (s) is preferably used for the present invention. Preferably, the carboxylic acid (s), such as lauric acid (C12), myristic acid (C14) or palmitic acid (C16) The acids are used alone or in combination. Advantageously, the carboxylic acid (s) is (are) used at levels as low as 8 or 7% by weight. and at levels as high as 11 or 12% by weight.
    Freeze-thaw Stabilizing Compounds [049] In a preferred embodiment, one or a mixture of
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    16/42 small hydrophobic compounds are preferably used in the present invention to stabilize the composition against substantial loss in viscosity during the freeze-thaw cycle. Useful compounds include branched Ce-C-alkenes, branched Ce-C-isols, branched Ce-C-alkanes, branched Ce-C-alkanes, alkyl aryl ethers
    Branched C6-C18, benzyl esters and mixtures thereof for maintaining at least 55% of the composition's viscosity after a freeze-thaw cycle using the standard freeze-thaw test described below.
    [050] Useful compounds include the following:
    (1) linalool
    (2) citronelo
    (4) limonene
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    (R)
    (5) polyoxyethylene isooctylphenyl ether (2)
    (6) lillial; 2- (4-tert-butylbenzyl) propionaldehyde
    (7) benzyl salicylate
    [051] Other suitable compounds include isooctanol, isotridecanol, and / or isodecanol and the like.
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    Cationic Skin Conditioning Agents [052] A useful component in the compositions according to the present invention is a cationic skin sensing agent or a polymer, such as, for example, cationic celluloses. Cationic polymers are preferably used at levels as low as about 0.1 to 2% to levels as high as the solubility limit of the specific polymer or, preferably, up to about 4 to 5% by weight, provided that the solubility limit of the particular cationic polymer or mixture is not exceeded.
    [053] Cationic cellulose is available from Amerchol Corp (Edison, NJ, USA) in its Polymer JR (trademark) and the LR polymer series (trademark), such as hydroxyethyl cellulose salts reacted with trimethyl-substituted epoxy ammonium, referred to in the industry (CTFA) as Polyquaternium 10. Another type of cationic cellulose includes the polymeric quaternary ammonium salts of hydroxyethyl cellulose reacted with the epoxide substituted by lauryl dimethyl ammonium, referred to in the industry (CTFA) as Polyquaternium 24. These materials are available from Amerchol Corp (Edison, NJ, USA) under the polymer trademark LM200.
    [054] A particularly suitable type of cationic polysaccharide polymer that can be used is a cationic guar gum derivative, such as hydroxypropyltrimonyium chloride guar (commercially available from Rhone-Poulenc in its Jaguar trademark series). Examples are the Jaguar (r) C13S, which has a low degree of substitution of cationic groups and high viscosity, Jaguar (r) C15, with a moderate degree of substitution and a low viscosity, Jaguar (r) C17 (high degree of substitution, high viscosity), Jaguar (r) C16, which is a hydroxypropylated cationic guar derivative containing a low level of groups
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    19/42 substituents, as well as groups of cationic quaternary ammonium, and Jaguar (r) 162, which is a medium viscosity guar of high transparency, with a low degree of substitution.
    [055] Particularly preferred cationic polymers are the Jaguar (r) C13S, Jaguar (r) C15, Jaguar (r) C17, Jaguar (r) C16 and Jaguar (r) C162, in particular the Jaguar C13S and Jaguar (r ) C-14 / BFG. The Jaguar (r) C14 / GAF material is the same molecule as the Jaguar (r) in C13, except that a glyoxal crosslinking agent has replaced boron. Other cationic skin agents known in the art can be used as long as they are compatible with the formulation of the present invention.
    [056] Other suitable examples of surfactants described above, which can be used are described in "Surface Active Agents and Detergents" (Vol. I and II) by Schwartz, Perry and Berch, incorporated by reference in their entirety.
    [057] In addition, the cleaning composition of the present invention can include from 0 to 15% by weight of the optional ingredients as follows: sequestering agents, such as tetrasodium ethylene diaminotetra acetate (EDTA), EHDP or mixtures in an amount of 0.01 to 1%, preferably 0.01 to 0.05%; and soluble coloring agents, and the like, all of which are useful in enhancing the appearance or cosmetic properties of the product.
    [058] The compositions can still comprise antimicrobials, such as methylisothiazolinone / methylchloroisothiazolinone (Kathon, MIT), dimethylaldimethylidantoin / iodopropynyl butylcarbamate (Glydant XL1000), parabens, sorbic acid, and the like.
    [059] The compositions may also comprise coconut acyl mono- or diethanol amides as foam enhancers and strongly ionizing salts, such as sodium chloride and sodium sulfate, too,
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    20/42 can advantageously be used to increase viscosity. Preferably, strongly ionizing salts, also known as electrolytes, will be present in amounts less than 5, 4, 3, or 1% by weight.
    [060] Antioxidants, such as, for example, butylated hydroxytoluene (BHT) and the like, can advantageously be used in amounts of about 0.01% or greater, if appropriate.
    Emollients [061] The term “emollient” is defined as a substance that softens or improves the elasticity, appearance and youth of the skin (stratum corneum), by increasing its water content, adding or replacing lipids and other skin nutrients; or both, and keeps it soft, slowing down the reduction of its water content.
    [062] Moisturizers that are also humectants, such as polyhydric alcohols, for example, glycerin and propylene glycol, and the like; and polyols, such as polyethylene glycols such as Polyox WSR N-60K (PEG45M) and the like are used in a preferred embodiment of the present invention. Humectants are preferably used at a minimum of 0.5, 2.5 or 5% by weight and a maximum of 15, 20 or 25% by weight.
    [063] Useful hydrophobic emollients include, but are not limited to, the following:
    (a) silicone oils and their modifications, such as linear and cyclic polydimethylsiloxanes; silicone oils of amino, alkyl, alkylaryl and aryl;
    (b) fats and oils, which include natural fats and oils (triglycerides), such as jojoba, soy, sunflower, rice bran, avocado, almond, olive, sesame, peach, castor, coconut, mink oils; cocoa fat; bovine tallow, lard; hardened oils obtained by hydrogenation
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    21/42 of the oils mentioned above; and synthetic mono-, di- and triglycerides, such as myristic glyceride acid and 2-ethylhexanoic glyceride acid;
    (c) waxes such as carnauba, spermaceti, beeswax, lanolin and their derivatives;
    (d) hydrophobic plant extracts;
    (e) hydrocarbons, such as petroleum jelly, polybutene, liquid paraffin, microcrystalline wax, ceresin, squalene, pristan and mineral oil;
    (f) higher alcohols, such as lauryl, cetyl, stearyl, oleyl, behenyl, cholesterol and 2-hexidecanol;
    (g) esters, such as cetyl octanoate, myristyl lactate, cetyl lactate, isopropyl myristate, myristyl myristate, isopropyl palmitate, isopropyl adipate, butyl oleate, decyl stearate, decyl oleate, decyl oleate cholesterol, glycerol monostearate, glycerol distearate, glycerol tristearate, alkyl lactate, alkyl citrate and alkyl tartrate;
    (h) essential oils and their extracts such as mint, jasmine, camphor, white cedar, bitter orange peel, ryu, turpentine, cinnamon, bergamot, citrus unshiu, calamus, pine, lavender, laurel, cloves, hiba, eucalyptus , lemon, evergreen, thyme, peppermint, rose, sage, sesame, ginger, basil, juniper, lemongrass, rosemary, rosewood, avocado, grape, grape seed, myrrh, cucumber, watercress, marigold , elderberry, geranium, linden flower, amaranth, seaweed, ginko, ginseng, carrot, guarana, tea tree, jojoba, comfrey, oats, cocoa, neroli, vanilla, green tea, mint, aloe vera, menthol, cineol, eugenol, citral , citronella, borneol, linalool, geraniol, primrose, camphor, thymol, spirantol, penene, limonene and terpenoid oils, (i) mixtures of any of the above components, and the like.
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    Optional Active Agents [064] Advantageously, active agents other than conditioning agents such as the emollients or moisturizers defined above can be added to the cleansing composition in a safe and effective amount during the formulation for skin treatment during use of the product. Suitable active ingredients include those that are water-soluble or are dispersible within the limits previously established. The appropriate active agents, advantageously, can be selected from the active anti-microbial and antifungal agents, vitamins, anti-acne actives; anti-wrinkles, anti-skin actives and skin repair; skin barrier repair assets; non-steroidal soft cosmetic assets; artificial tanning agents and accelerators; skin lightening assets; sunscreen assets; tallow stimulants; sebum inhibitors; antioxidants; protease inhibitors; skin tightening agents; anti-itch ingredients; hair growth inhibitors; 5-alpha reductase inhibitors; enhancers of peeling enzymes; anti-glycation agents; topical anesthetics, or mixtures thereof; and the like.
    [065] These active agents can be selected from water-soluble active agents, oil-soluble active agents, pharmaceutically acceptable salts and mixtures thereof. Advantageously, the agents will be soluble or dispersible in the cleaning composition. The term "active agent", as used herein, means active personal care agents that can be used to provide a benefit to the skin and / or hair and that, in general, are not used to confer a conditioned benefit as is. conferred by humectants and emollients previously described in the present. The term "safe and effective amount", as used herein, means an amount of active agent high enough to modify the condition to be treated or to provide the desired benefit of
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    23/42 skin care, but low enough to avoid serious side effects. The term "benefit", as used herein, means the therapeutic, prophylactic and / or chronic benefits associated with treating a condition, in particular, with one or more of the active agents described herein. What is a safe and effective amount of the active agent ingredient will vary with the specific active agent, the ability of the active ingredient to penetrate through the skin, the consumer's age, health and skin condition, and other similar factors. Preferably, the composition of the present invention comprises from about 0.01% to about 25%, more preferably, from about 0.05% to about 15%, most preferably 0 , 1% to about 10%, and, even more preferably, from 0.1% to about 5%, by weight the active agent component.
    [066] Anti-acne actives can be effective in treating common acne, a chronic disease of the pilosebaceous system. Non-limiting examples of useful anti-acne assets include keratolytics, such as salicylic acid (o-hydroxybenzoic acid), salicylic acid derivatives such as 5-octanoyl salicylic acid and 4 methoxysalicylic acid, and resorcinol; retinoids such as retinoic acid and its derivatives (for example, cis and trans); sulfur-containing amino acids D and L and their derivatives and salts, particularly their N-acetyl derivatives, mixtures and the like.
    [067] Antimicrobial and antifungal actives can be effective in preventing the proliferation and growth of bacteria and fungi. Non-limiting examples of antimicrobial and antifungal actives include blactamic drugs, quinolone drugs, ciprofloxacin, norfloxacin, tetracycline, erythromycin, amikacin, 2,4,4'-trichloro-2'-hydroxy diphenyl ether, 3,4,4 trichlorobanilide, phenoxyethanol, triclosan; triclocarban; and their mixtures and the like.
    [068] Anti-Wrinkle, Anti-Skin Aging And Skin Repair Assets
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    24/42 can be effective in replacing or rejuvenating the epidermal layer. These assets, in general, provide these desirable skin care benefits by promoting or maintaining the natural peeling process. Non-limiting examples of anti-wrinkle and anti-skin actives include skin vitamins, minerals and nutrients, such as milk, vitamins A, E and K; alkyl esters, vitamin, which include the alkyl esters of vitamin C; magnesium, calcium, copper, zinc and other metallic components; retinoic acid and its derivatives (for example, cis and trans); retina; retinol; retinyl esters, such as retinol acetate, retinol palmitate, and retinyl propionate; vitamin B 3 compounds (such as niacinamide and nicotinic acid), alpha hydroxy acids, beta hydroxy acids, for example, salicylic acid and its derivatives (such as 5-octanoyl salicylic acid, heptyloxy 4 salicylic acid, and salicylic acid 4-methoxy); mixtures and the like.
    [069] Skin barrier repair assets are skin care assets that can help repair and replenish the epidermis natural moisture barrier function. Non-limiting examples of skin barrier repair assets include lipids, such as cholesterol, sucrose esters, ceramides and pseudoceramides, as described in European patent specification 556,957; Ascorbic acid; biotin; biotin esters; phospholipids, their mixtures and the like.
    [070] Soft active non-steroidal cosmetics can be effective in preventing or treating inflammation of the skin. The mild active enhances the skin appearance benefits of the present invention, for example, such agents contribute to a more uniform and acceptable skin tone or color. Non-limiting examples of mild cosmetic agents include the following categories: propionic acid derivatives; acetic acid derivatives; derivatives of phenamic acid; mixtures and the like. Many of these mild cosmetic active agents are described in US patent 4,985,459 to
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    Sunshine et al., Filed on January 15, 1991, incorporated herein as a reference in its entirety.
    [071] The assets for artificial tanning can assist in the simulation of a natural tan, through the increase of melanin in the skin or through the increased production of the appearance of melanin in the skin. Non-limiting examples of artificial tanning agents and accelerators include dihydroxyacetone; tyrosine; tyrosine esters such as ethyl tyrosinate and glucose tyrosinate; their mixtures, and the like.
    [072] Skin whitening actives can actually reduce the amount of melanin in the skin or provide such an effect through other mechanisms. Non-limiting examples of skin whitening assets useful in the present invention include aloe extract, alpha-glyceryl-lascorbic acid, aminothyroxine, ammonium lactate, glycolic acid, hydroquinone, 4-hydroxyanisole, mixtures thereof, and the like.
    [073] Sunscreen assets are also useful in the present invention. A wide variety of sunscreen agents are described in US patent 5,087,445, to Haffey et al, filed February 11, 1992; US patent 5,073,372, to Turner et al., filed December 17, 1991; US patent 5,073,371, to Turner et al., filed December 17, 1991; and Segarin, et al., in Chapter VIII, pages 189 et seq., of Cosmetics Science and Technology, all of which are incorporated herein as a reference in their entirety. Non-limiting examples of sunscreens that are useful in the compositions of the present invention are those selected from the group consisting of methoxy octyl cinnamate (Parsol MCX) and butylmethoxy benzoylmethane (Parsol 1789), p-methoxycinnamatode2-ethyl- hexyl, N, N-dimethyl-p-aminobenzoate of 2-ethylhexyl, p-aminobenzoic acid, 2-phenylbenzimidazole-5-sulfonic acid, oxybenzone, mixtures thereof, and the like.
    [074] Sebum stimulants can increase the production of
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    26/42 sebum by the sebaceous glands. Non-limiting examples of sebum-stimulating actives include brionolic acid, dehydroepiandrosterone (DHEA) and oryzane, mixtures thereof, and the like.
    [075] Sebum inhibitors can reduce sebum production by sebaceous glands. Non-limiting examples of sebum-inhibiting assets include aluminum chloride hydroxy, corticosteroids, dehydroacetic and its salts, dichlorophenyl imidazoldioxolan (available from Elubiol), mixtures thereof, and the like.
    [076] Protease inhibitors are also useful as active ingredients in the present invention. Protease inhibitors can be divided into two general classes: proteinases and peptidases. Proteinases act on specific internal peptide bonds of proteins and peptidases act on peptide bonds adjacent to a free amino or a carboxyl group at the end of a protein and therefore cleaves the protein from the outside. Protease inhibitors suitable for use in the present invention include, but are not limited to, proteases, such as serine proteases, cysteine proteases, metalloproteases, and aspartyl proteases, and peptidases, such as carboxypepidases, and dipeptidase aminopepidases, mixtures and the like.
    [077] Other active ingredients useful in the present invention are skin tightening agents. Non-limiting examples of skin-firming agents that are useful in the compositions of the present invention include monomers that can bind a polymer to the skin, such as vinylpyrrolidone, (meth) acrylic acid and a hydrophobic (met) compound monomer long chain alkyl acrylates, mixtures thereof, and the like.
    [078] The active ingredients of the present invention can also include anti-itch ingredients. Suitable examples of anti-itch ingredients that are useful in the compositions of the present invention include the
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    27/42 hydrocortisone, metdilazine and trimeprazine, their mixtures, and the like.
    [079] Non-limiting examples of hair growth inhibitors, which are useful in the compositions of the present invention include 17beta-estradiol, antiangiogenic steroids, Curcuma extract, cyclooxygenase inhibitors, evening primrose oil, linoleic acid and the like. Suitable 5alpha reductase inhibitors, such as ethinyl estradiol and genistin, their mixtures, and the like.
    [080] Non-limiting examples of enzyme peeling enhancers that are useful in the compositions of the present invention include alanine, aspartic acid, N-methyl serine, serine, trimethyl glycine, mixtures thereof, and the like.
    [081] A non-limiting example of an anti-glycation agent, which is useful in the compositions of the present invention would be Amadorine (available from Barnet Products Distributor), and the like.
    Optical Solid Particle Modifiers [082] A useful optional component of the compositions according to the present invention is one or more optical modifiers of solid particles, preferably reflecting the light of the platelet- or platy-shaped particles. These particles preferably have an average D50 particle size ranging from about 25,000 to about 150,000 nm. For plate-type materials, the average particle size is an average value in number. Platelets are assumed to have a circular shape with the diameter of the average circular surface over many particles. The thickness of the plate-like particles is considered to be a separate parameter. For example, platelets can have an average particle size of 35,000 nm and an average thickness of 400 nm. For the present purposes, the thickness is considered to vary from about 100 to about 600 nm. The scattering of laser light can be used for measurement,
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    28/42 except that the light scattering data must be mathematically corrected from the spherical to the non-spherical format. Optical and electron microscopy can be used to determine the average particle size. The thickness is usually only determined through optical or electron microscopy.
    [083] The refractive index of these particles can be at least about 1.8, in general, about 1.9 to about 4, for example, from about 2 to about 3, and between about 2.5 and 2.8.
    [084] Illustrative, but not limiting, examples of light-reflecting particles are bismuth oxychloride (which includes, for example, unique crystalline platelets), and titanium dioxide and / or mica-coated iron oxide. Suitable bismuth oxychloride crystals are available from EM Industries, Inc. under the trademarks Biron® NLY-L-CO 2X and Biron® Silver CO (where the platelets are dispersed in castor oil); Biron ® Liquid Silver (where the particles are dispersed in a stearate ester); and Nailsyn ® I GO, Nailsyn ® II C2X and Nailsyn ® II Platiem um 25 (where the platelets are dispersed in nitrocellulose). Most preferably, it is a system in which bismuth oxychloride is dispersed in a C2-C40 alkyl ester, such as in Biron® Liquid Silver.
    [085] Among the suitable titanium dioxide coated with mica platelets are the materials available from EM Industries, Inc. These include Timiron® MP-45 (particle size range from 49,000 to 57,000 nm),
    Timiron ® MP-99 (particle size range from 47,000 to 57,000 nm),
    Timiron ® MP-47 (particle size range from 28,000 to 38,000 nm),
    Timiron® MP-149 (particle size range from 65,000 to 82,000 nm), and Timiron® MP-18 (particle size range from 41,000 to 51,000 nm).
    The weight ratio of the coated titanium dioxide to the mica platelets can vary from about 1:10 to about 5: 1, preferably from
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    About 1: 6 to about 1: 7 by weight. Advantageously, the compositions will, in general, be substantially free of titanium dioxide other than that required for the mica coating.
    [086] Among the suitable iron oxide and titanium dioxide coated with mica platelets are the materials available from EM Industries, Inc. These include Timiron® MP-28 (particle size range from 27,000 to 37,000 nm), Timiron ® MP-29 (particle size range from 47,000 to 55,000 nm), and Timiron® MP-24 (particle size range from 56,000 to 70,000 nm).
    [087] Among the suitable iron oxide - coated mica platelets are materials available from EM Industries, Inc. These include Colorona Bronze Sparkle (particle size range 28000-42000 nm) Colorona Glitter Bronze ® (range particle size from 65,000 to 82,000 nm), Colorona ® Copper Sparkle (particle size range from 25,000 to 39,000 nm), and Colorona® Glitter Copper (particle size range from 65,000 to 82,000 nm).
    [088] Coatings suitable for mica other than titanium dioxide and iron oxide can also achieve the optical properties suitable for the present invention. These types of coated micas must also satisfy the refractive index of at least about 1.8. Other coatings include silica on the mica platelets
    Exfoliating [089] The composition of the present invention can contain particles larger than 50 microns in average diameter that help to remove dry skin. Without being restricted to theory, the degree of exfoliation depends on the size and morphology of the particles. Large, coarse particles are generally very stiff and irritating. Very small particles cannot serve as effective exfoliators. Such exfoliants used in the state of
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    Technical 30/42 include natural minerals, such as silica, talc, calcite, pedrapomes, tricalcium phosphate; seeds, such as rice, apricot seeds, and the like; crushed shells, such as almond and nut shells; oats; polymers such as polyethylene and polypropylene spheres, flower petals and leaves; microcrystalline wax spheres; jojoba ester beads, and the like. These scrubs come in a variety of particle sizes and morphology ranging in size from a micron to a few millimeters. They also have a hardness range. Some examples are provided in Table A below.
    Table A
    Material Hardness (Mohs) Baby powder 1 Calcite 3 Pumice 4-6 Nutshells 3-4 Dolomite 4 Polyethylene ~ 1
    [090] The present invention will now be described in greater detail by means of the following non-limiting Examples. The examples are for illustrative purposes only and are not intended to limit the present invention in any way. The physical test methods are described below:
    [091] Except for comparative and operational examples, or when otherwise expressly indicated, all numbers in this description indicating the quantities or proportions of materials or conditions or reaction, physical properties of materials and / or use, should be understood as modified by word “about”.
    [092] When used in the specification, the term “comprises” whenever used in this document is intended to include the presence of
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    31/42 characteristics, integers, stages, components indicated, but does not exclude the presence or addition of one or more characteristics, integers, stages, components or their groups.
    [093] All percentages in the specification and examples are intended to be, by weight, unless otherwise stated.
    Examples
    Example 1 [094] Several compositions of the present invention and comparatives were prepared according to Table 1 and the dilution profile and foam profile were measured for each one, according to the methods provided below. The data are listed in Table 2.
    [095] The compositions of the present invention, showed that, with the addition of lauric acid in a proportion of synthetic anionic surfactant (s) + fatty acid (s) of cotensoative (s): of about 2 at 6, the viscosity built up by dilution was reduced or only slightly increased, therefore improving the speed for foam and foam volume.
    Table 1
    Ingredients Sample Sample Sample of Sample ofComparative Comparative gift gift1 2 invention 3 invention 4 Sodium lauryl sulfate ether (1) 20 20 20 20 Sodium lauroyl anfoacetate(2) 10 10 10 10 Lauric acid (3) 0 3 5 9 Water up to 100 up to 100 up to 100 up to 100
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    Ingredients SampleComparative1 SampleComparative2 Sample of the present invention 3 Sample of the present invention 4 Proportion of synthetic anionic surfactant (s): cotensoative (s) 2 2 2 2 Ratio of synthetic anionic surfactant (s) and synthetic anionic (s) to the linear C12-C18 alkyl fatty acid (s) Undefined 10 6 3.33
    (1) Sodium lauryl sulfate ether (trade name: Texapon N701) obtained from BASF (Florham Park, NJ 07932, USA) (2) Sodium lauroyl anfoacetate (trade name: Miranol Ultra G-
    32) obtained from Rhodia (8 Cedar Brook Drive, Cranbury, NJ 08.512-7.500, USA) (3) Lauric acid (trade name Edenor C12-98-100) obtained from
    Emery Oleochemicals (4900 Este Avenue, 45232 Cincinnati, Ohio, USA)
    Table 2
    Viscosity (Pa.s) at 1 1 / s Concentration of Sample Sample surfactant, which includes LA gives gives (percentage (%) in Sample Sample gift gift weight) (details on Comparative Comparative invention invention Table 1) 1 2 3 4 39 130 35 32.13312.6
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    Viscosity (Pa.s) at 1 1 / s Surfactant concentration, which includes LA (percentage (%) by weight) (details in Table 1) SampleComparative1 SampleComparative2 Sample of the present invention3 Sample of the present invention4 30 1.73 20 1.64 0.556 0.268 0.817 15 104 3.61 0.538 0.0596 7 0.272 0.088 0.0133 0.031 Speed toFoam (on a scale of 5) 2 2 4 5 Amount of foam(on a scale of 5) 2 3 4 5
    Example 2 [096] A series of samples was prepared as shown in Table 3, with the thawing and freezing stabilizers of the present invention, shown in Table 4 and in comparison with the comparative materials, as shown in Table 5. It was observed that the defrost and freeze stabilizers of the present invention provide protection against a drop in viscosity of not more than 55% using the freeze-thaw method described below.
    Preparation method [097] All Formulas in Tables 1 to 3, 6 and 8 were prepared using the following procedure:
    (1) Add water and fatty acid (s) (which includes acid
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    34/42 hydroxyl stearic, if present) and heat to 80 ° C (2) Add polyols such as PPG-9 (3) Mix until all the fatty acid (s) are melted (4 ) Add the primary synthetic anionic surfactant and mix until uniform (5) Add the secondary co-active (s) and mix until uniform (6) Add optional emollients and occlusive agents (7) Start reducing temperature (8) Add the freezing and thawing additives to
    60 ° C (9) Add preservatives and fragrances below 40 ° C (10) Cool and mix until homogeneously uniform
    Table 3
    Formulation Details: Sample A Formula
    Ingredients Percentage(%) by weight Sodium lauryl sulfate ether 20 Sodium lauroyl Anfoacetate (AA) 10 Lauric acid 9 PPG-9 2 Freezing and thawing additives 0-5 Proportion of synthetic anionic surfactant (s): cotensoative (s) 2 Ratio of synthetic anionic surfactant (s) and synthetic anionic (s) to the linear C12-C18 alkyl fatty acid (s) 3.33
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    Table 4 [098] Shows the Examples containing a selection of compounds of the present invention that provide freeze-thaw stability when present at levels of 2 to 3% of a typical lamellar concentrated composition provided in Table 3
    Additive PercentageViscosity at Percentage freezing- (%) (F / T) of Viscosity RT * after 1 (%) of the fall thawing additive in at RT (10 Hz) F / T cycle at (F / T) Sample A - Pa, s (10Hz) - Pa, s viscosity Dihydromyrcenol 2 13.5 11.6 14 Isodecanol 2 12.4 10.4 16 Isooctanol 2 14.2 11.6 18 Isotridecanol 2 13.4 10.6 21 Linalol 2 13.5 10.5 22 Citronelol 2 20.1 14.9 26 1-octene-3-ol 2 17.3 12.6 27 Hexyl acetate 2 19.3 12.9 33 Limonene 2 16.5 10.9 34 Ether of polyoxyethylene (2) isooctylphenyl (Igepal CA-210) 2 12.5 8.05 36 Lillial 2 17.4 11.1 36 Hexane 2 14.1 8.77 38 1-Octene 2 13.4 8.22 39 Salicylate benzila 2 19.9 9.1 54
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    36/42 * RT = room temperature or about 22 ° C
    Table 5 [099] Shows the Examples containing a selection of comparative compounds that do not provide substantial freeze-freeze stability (compared to a “no additive” control), when present at 2 to 3% levels in a typical concentrated lamellar composition provided in Table 3
    Percentage (%) by weightViscosity at Percentage Additive (F / T) of Viscosity RT after 1 cycle (%) of the fall freezing- additive in to RT (10 F / T (10Hz) - at thawing (F / T) Sample A Hz) - Pa, s Pa, s viscosity Octane 2 14.1 3.34 76 Octanol 2 20.7 4.58 78 Lauryl alcohol 2 38.6 2.95 92 2-ethylhexyl sulfate sodium 2 8.6 0.631 93 Dipropylene glycol (DPG) 2 12.2 0.53 96 Xylene sulphonate sodium 0.5 16.1 0.616 96 Without additive 0 11.8 0.302 97 Dean 2 25.1 0.546 98 Sorbitol 3 17.6 0.376 98 Isostearyl alcohol 2 37.2 0.769 98 Oleic acid 2 27.7 0.388 99 Capric triglyceride caprylic (CCT) 2 66 0.907 99
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    Example 3 [0100] A series of samples of the present invention and comparative in another preferred embodiment of the present invention, provided in Table 6 was prepared with the hydroxy stearic acid and the freezing and thawing stabilizing materials of the present invention and in comparison with the same samples with the comparative material (s) as described in Table 7. All freeze and thaw stabilizing materials of the present invention were observed to provide protection against a drop in viscosity of not more than 55 %, even in formulations containing hydroxy stearic acid (Sample Formula B), using the freeze-thaw method described below.
    Table 6
    Formulation Details: Sample B Formula
    Ingredients Percentage(%) by weight Sodium lauryl sulfate ether 20 Sodium lauroyl Anfoacetate (AA) 10 Lauric acid 9 12-hydroxystearic acid 2 PPG-9 2 Freezing and thawing additives 0-5 Proportion of synthetic anionic surfactant (s): cotensoative (s) 2 Ratio of synthetic anionic surfactant (s) and synthetic anionic (s) to the linear C12-C18 alkyl fatty acid (s) 3.33
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    Table 7 [0101] Shows a sampling of well-known freeze-thaw additives comparing the Examples of the present invention and the Comparative Examples (and a control) in a lamellar concentrated composition with hydroxyl stearic acid as in Formula B sample
    Defrosting freezing additive (F / T) Percentage (%) (F / T) of additive in Sample B Viscosity at RT (10 Hz)- Pa, s Viscosity at RT after 1 F / T cycle (10Hz) -Pa, s Percentage (%) of drop in viscosity Dihydromyrcenol 2 13.5 11.6 14 DPG 2 75.4 0.753 99 Lauryl alcohol 2 38.6 2.95 92 NaCl 1.5 25.4 0.907 96 Without additive (Control) 0 12.2 0.881 93
    Example 4 [0102] A series of samples from another preferred embodiment of the present invention was prepared as indicated in Table 8 with the thawing and freezing stabilizers of the present invention shown in Table 9 and in comparison with the comparative materials, as shown in Table 10 It has been observed that the defrost and freeze stabilizers of the present invention provide protection against a drop in viscosity of not more than 55% using the freeze-thaw method described below.
    Table 8 [0103] Shows another preferred embodiment of the present
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    39/42 invention, containing 25% by weight. From petroleum jelly:
    Ingredients Percentage(%) Sodium lauryl sulfate ether 15 Sodium lauroyl Anfoacetate (AA) 7.5 Lauric acid 6.75 Vaseline 25 PPG-9 1.5 Dihydromyrcenol 2 Proportion of synthetic anionic surfactant (s): cotensoative (s) 2 Proportion of synthetic anionic surfactant (s) and cotensoative (s)for C12-C18 alkyl linear fatty acid (s) 3.33
    Table 9 [0104] Shows the selected properties of some of the freeze-thaw materials of the present invention that provide substantial freeze-thaw stability in the concentrated lamellar compositions of the present invention.
    Freezing and thawing additive Mol, inWeight ValueHLB Length (in Angstroms) Melting point (C) Dihydromyrcenol 156 0.69 11.93 -24.41 Isooctanol 130 1.89 11.53 -76 Isotridecanol 200 1.89 19.04 <-30 1 -Octene-3-ol 128 2.36 12.85 -49.17 Igepal CA-210 294 2.7 13.6Hexane 86 <1 10.4 -96 1 -Ocene 112 <1 12.77 -107
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    Table 10 [0105] Shows the selected properties of some of the comparative materials that do not provide the amount of freeze-thaw stability in the concentrated lamellar compositions of the present invention.
    Additive freezing and thawing Mol, inWeight ValueHLB Length (in Angstroms) Melting point (C) Lauryl alcohol 186 2.13 19.04 24 Sodium 2-ethylhexyl sulfate 232 24.82 14.13 > 15 SXS (sodium xylene sulfonate 208 25.26 10.96 27 Sorbitol 182 > 20 10.94 95 Isostearyl alcohol 270 1.04 25.32 0 Oleic acid 282 1.61 25.91 13
    Methods (A) Foaming method [0106] The foam was manually generated using water at 37 ° C. The following protocol was used:
    (a) 1.5 grams of product were dosed in wet hands;
    (b) 2 g of additional water was used to dilute and both hands were rubbed back and forth five times to generate foam;
    (c) foam velocity was assessed qualitatively based on the number of rubs required for foam generation (usually visually assessed after 5 rubs);
    (d) more water was added to generate more foam and after
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    41/42 to 15 of scrubbing, the foam was collected and visually evaluated for the amount of foam on a scale of 1 to 5, where 1 represents no visible foam and 5 represents abundant foam.
    (B) Rheology Method [0107] The following method was used to determine viscosity.
    [0108] The viscosities of the samples during the dilution process were measured at a shear rate of 1 1 / s using a standard experiment scan rate of 0.1 to 100 1 / s. A 50 mm serrated cone with a 2 ° cone angle was used for measurements and the experiments were carried out in a standard tension controlled rheometer (MCR 300 manufactured by Anton Paar), at room temperature or about 22 o C.
    (C) Freeze-thaw method [0109] A fast scan rheological measurement was developed to determine the effectiveness of freeze-freeze additives on viscosity. The samples were loaded and the temperature scanning experiments, with a constant frequency of 10 Hz and a constant voltage of 1%, were carried out in a MCR 300 controlled voltage rheometer, manufactured by Anton Paar, using the 50 mm serrated cone with the cone angle of 2 ° in a fixed gap of 0.213 mm. Three temperature cycles were performed on each sample: (i) the refrigeration cycle from RT (room temperature) to 4 o C (ii) the heating cycle from 4 o C to 50 o C, and (iii ) the cooling cycle again from 50 o C to room temperature. The data were collected at 2 o C intervals and at each temperature, the sample was left to equilibrate for 1 min. The change in viscosity was determined from the initial viscosity of room temperature to the viscosity of the sample at
    Petition 870190100374, of 10/07/2019, p. 52/103
    42/42 room temperature after passing through the first cooling cycle.
    [0110] Although the present invention has been described in relation to its special embodiments, it is evident that in numerous other forms and modifications of the present invention it will be obvious to those skilled in the art. The appended claims and the present invention, in general, must be constructed to encompass all of these obvious forms and modifications that are within the true spirit and scope of the present invention.
    权利要求:
    Claims (16)
    [1]
    Claims
    1. SKIN CLEANING COMPOSITION, aqueous, structured lamellar, characterized by comprising:
    (a) 15 to 40% by weight of synthetic anionic surfactant (s);
    (b) 5 to 30% by weight of co-surfactant (s) selected from the group of amphoteric or non-ionic surfactants or mixtures thereof;
    (c) 5 to 15% by weight of C12-C18 alkyl linear fatty acid (s);
    (d) in which the proportion of synthetic anionic surfactant (s): co-surfactant (s) is 0.5 to 3; and (e) where the proportion of synthetic anionic surfactant (s) and co-surfactant (s) to the linear alkyl fatty acid (s) C12-C18 is 2 to 6.
    [2]
    2. COMPOSITION according to claim 1, characterized in that the viscosity continually reduces or increases by not more than 3 Pa.s, as the composition is diluted with water at 40 ° C during cleaning and rinsing of the skin by a consumer .
    [3]
    COMPOSITION according to any one of claims 1 to 2, characterized in that the pH is in the range of 5 to 8.
    [4]
    COMPOSITION according to any one of claims 1 to 3, characterized in that it also comprises an effective amount of freeze-thaw stabilizer (s) selected from branched C6-C18 alkenes, branched C6-C18 alkenes, branched C6-C18 alkanols, branched C6-C18 alkanes, branched C6-C18 alkylaryl ethers, benzyl esters and mixtures thereof to maintain at least 55% of the composition's viscosity after a freeze-thaw cycle using the standard freeze-thaw test .
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    2/3
    [5]
    COMPOSITION according to claim 4, characterized in that the freeze-thaw stabilizer (s) is present in a total concentration of 0.5 to 5% by weight.
    [6]
    6. COMPOSITION according to any one of claims 4 to 5, characterized in that the freezing defrost stabilizer (s) is selected from dihydromyrcenol, isooctanol, linalool, citronellol, 1-octene-3 -ol, hexyl acetate, limonene, octylphenoxy polyethoxy ethanol (igepal), lillial, hexane, 1-octene and benzyl salicylate or mixtures thereof.
    [7]
    COMPOSITION according to any one of claims 4 to 6, characterized in that the freeze-thaw stabilizer (s) has an HLB value of less than 5.
    [8]
    COMPOSITION according to any one of claims 4 to 7, characterized in that the freeze-thaw stabilizer (s) has (in) an effective molecular length greater than 5 but not exceeding 30 Angstroms.
    [9]
    COMPOSITION according to any one of claims 4 to 8, characterized in that the freezing defrost stabilizer (s) has a melting point below 0 o C.
    [10]
    COMPOSITION according to any one of claims 1 to 9, characterized in that it further comprises 0.5 to 3% by weight of 12-hydroxy stearic acid.
    [11]
    COMPOSITION according to any one of claims 1 to 10, characterized in that it also comprises non-occlusive emollients in the concentration range of 0.5 to 25% by weight.
    [12]
    12. COMPOSITION, according to claim 11, characterized in that the non-occlusive emollients are selected from glycerin, 1,3-butanediol, or mixtures thereof.
    Petition 870190100374, of 10/07/2019, p. 55/103
    3/3
    [13]
    13. COMPOSITION according to any one of claims 1 to 12, characterized in that it also comprises occlusive emollients in the concentration range of 0.5 to 25% by weight.
    [14]
    14. COMPOSITION, according to claim 13, characterized by the occlusive emollients being selected from mineral oils, tri and diglyceride oils, silicone oils, petroleum jelly, paraffin wax or mixtures thereof.
    [15]
    15. COMPOSITION according to any one of claims 1 to 14, characterized in that the synthetic anionic surfactants are selected from sodium lauryl sulfate ether - 1EO, 2EO or 3 EO, C12 acyl glycinate, directly esterified fatty isethionate (DEFI ) or sodium trideceth sulfate, or mixtures thereof.
    [16]
    16. COMPOSITION according to any one of claims 1 to 15, characterized in that the co-surfactant (s) is (are) selected from cocoamidopropyl betaine, sodium lauroyl anfoacetate, hydroxyl cocamidopropyl sultaine, alkyl polyglucoside or mixtures thereof.
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    同族专利:
    公开号 | 公开日
    BR112015013023A2|2018-04-24|
    US8778910B2|2014-07-15|
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    法律状态:
    2018-05-08| B06F| Objections, documents and/or translations needed after an examination request according art. 34 industrial property law|
    2019-07-16| B07A| Technical examination (opinion): publication of technical examination (opinion)|
    2019-10-15| B09A| Decision: intention to grant|
    2019-11-05| B16A| Patent or certificate of addition of invention granted|Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 18/11/2013, OBSERVADAS AS CONDICOES LEGAIS. |
    2021-02-09| B25A| Requested transfer of rights approved|Owner name: UNILEVER IP HOLDINGS B.V. (NL) |
    优先权:
    申请号 | 申请日 | 专利标题
    US13/708,012|US8778910B2|2012-12-07|2012-12-07|Concentrated lamellar liquid personal cleansing composition|
    PCT/EP2013/074076|WO2014086576A1|2012-12-07|2013-11-18|Concentrated lamellar liquid personal cleansing composition|
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